(a) Optoplasmonic single-molecule sensor scheme, experimental setup, and resonance profiles with shifts due to the TOP effect. (b) extinction spectrum of the GNR used in the experiments; (c) Examples of measured resonance wavelength under the attachment of 3-phosphoglycerate kinase (3PGK) molecules. Red and blue shifts are recorded for low and high intensities inside the WGM, respectively. Reproduced from [104].