The second generation of multiphoton tomographs MPTflex is easy to move and possesses an optical arm with a 360° measurement head. The MPTflex received the certificate of conformity as a medical device in 2010. Left: “conventional” MPTflex with two PMT detectors. Right: Two-beam multiphoton tomograph MPTflex-CARS with four PMT detectors to measure simultaneously time-resolved autofluorescence, SHG, and Raman signals of lipids/water.