| Issue |
J. Eur. Opt. Soc.-Rapid Publ.
Volume 9, 2014
|
|
|---|---|---|
| Article Number | 14019 | |
| Number of page(s) | 10 | |
| DOI | https://doi.org/10.2971/jeos.2014.14019 | |
| Published online | 01 June 2014 | |
Regular papers
Waveguide structures for efficient evanescent field coupling to zero mode waveguides
1
Optics Research Group, Delft University of Technology, Lorentzweg 1. 2628 CJ Delft, The Netherlands
2
Institut d’Optique Graduate School, 2 Avenue Augustin Fresnel, 91127 Palaiseau, France
3
Philips Research Laboratories, High Tech Campus 34, 5656 AE Eindhoven, The Netherlands
Received:
25
February
2014
Revised:
29
April
2014
The use of waveguide structures is examined to improve the efficiency of evanescent field coupling into zero-mode waveguides. Model calculations show that waveguide excitation using diffractive structures, increases the magnitude of the evanescent electric field by an order of magnitude compared to far field excitation of the evanescent field. A more efficient excitation of fluorescent markers used in e.g. sequencing instrumentation ultimately enables real-time single molecule detection using laser systems with moderate output power.
Key words: Zero mode waveguide / DNA sequencing / waveguide structure / grating structure / finite element methods
© The Author(s) 2014. All rights reserved.
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